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Brand name: Avelox ,Actira
Generic name: Moxifloxacin Hydrochloride
Why is Actira prescribed ?
Actira, an antibiotic, is prescribed to treat sinus and lung
infections. It kills bacteria that can cause sinusitis, pneumonia,
and secondary infections in chronic bronchitis. It also fights
skin infections caused by staph or strep. Actira is a member
of the quinolone family of antibiotics. Like all antibiotics,
Actira works only against bacteria. It will not cure an infection
caused by a virus.
Most important fact about Actira
In rare cases, antibiotics can cause a serious allergic reaction.
Stop taking Actira and call your doctor immediately if you
develop any of the following warning signs: skin rash, tingling,
hives, shortness of breath, swelling of the face or throat,
or difficulty swallowing.
How should you take Actira ?
Actira may be taken with or without food. Even if you feel
better, finish taking all the Actira that has been prescribed
for you. If you stop taking Actira too soon, surviving bacteria
could cause a relapse.
Be sure to drink plenty of fluids while taking Actira.
If you miss a dose of Actira
Take it as soon as you remember. If it is almost time for
your next dose, skip the one you missed and go back to your
regular schedule. Do not take a double dose in an effort to
"catch up."
Storage instructions for Actira
Store Actira at room temperature. Avoid high humidity.
What side effects may occur when taking Actira ?
Most people taking Actira do not experience side effects;
and when reactions do occur, they are usually mild. If you
do develop a side effect, however, inform your doctor as soon
as possible. Only your doctor can determine if it is safe
for you to continue taking Actira.
More common side effects of taking Actira may include:
Nausea, diarrhea, dizziness
Less common side effects of taking Actira may include:
Abdominal pain, indigestion, headache, abnormal taste, vomiting
Rare side effects of taking Actira may include:
Allergic reaction (occasionally severe), anxiety, appetite
loss, bladder infection, blood clotting changes, back pain,
body pain, breathing difficulties, chest pain, chills, confusion,
constipation, cough, digestive system disorders, dim vision,
drowsiness, dry mouth, dry skin, fungal infections, gassiness,
hallucinations, hand pain, high blood pressure, high blood
sugar, incoordination, increased cough, insomnia, irregular
heartbeat, itching, joint pain, labored breathing, leg pain,
low blood pressure, mouth sores, nasal inflammation, nervousness,
personality changes, pneumonia, rapid heartbeat, rash, sinus
inflammation, sore throat, stomach irritation, sweating, swelling,
tingling or burning sensations, tongue inflammation, tremors,
urinary inflammation, vaginal inflammation, vague feeling
of illness, vertigo, weakness andyellow eyesn. A variety of
other extremely rare side effects have been reported. Check
with your doctor if any new or unusual symptoms develop.
Why should Actira not be prescribed ?
If you have ever had an allergic reaction to any other quinolone
antibiotic, such as Cipro, Floxin, Levaquin, Maxaquin, Noroxin,
or Penetrex, you should not take Actira.
Special warnings about Actira
Actira may make you dizzy or light-headed. Do not drive a
car, operate machinery, or engage in activities requiring
mental alertness or coordination until you know how Actira
affects you.
Actira can cause certain heart irregularities in people already
prone to the problem. If you are being treated for an abnormal
heartbeat, make sure the doctor is aware of it. You may have
to avoid Actira. Also tell the doctor if you or anyone in
your family has a history of heart problems. If you develop
palpitations or fainting spells while taking Actira, contact
your doctor immediately.
Before you take Actira, you should tell your doctor if you
have a history of convulsions or blockage of the arteries
in the brain. Quinolone-type antibiotics like Actira have
been known to cause convulsions and other problems with the
nervous system, including symptoms such as agitation, anxiety,
dizziness, confusion, depression, hallucinations, nervousness,
nightmares, tremors, and suicidal thoughts. Contact your doctor
immediately if you experience any of these reactions.
Actira also may cause Achilles and other tendon ruptures,
especially in older adults and those taking steroids. If you
experience pain or inflammation in a tendon contact your doctor.
Like other antibiotics, it can also cause serious intestinal
inflammation. If you develop diarrhea, let your doctor know
immediately.
Actira can make your skin more sensitive to light, so you
should avoid excess sunlight and tanning beds.
You should avoid Actira if you have a low level of potassium
in your blood. Low potassium can be caused by the water pills
(diuretics) often prescribed for high blood pressure. If you
are taking a diuretic, make sure the doctor knows about it
before you begin treatment with Actira.
A case of diarrhea during Actira therapy could signal development
of a potentially dangerous bowel inflammation. Call your doctor
for treatment at the first sign of a problem.
Actira has not been tested in children under 18.
Possible food and drug interactions when taking Actira
Multivitamins containing iron or zinc; antacids containing
magnesium, calcium, or aluminum; Carafate (sucralfate); or
Videx (didanosine) reduce the effectiveness of Actira. Take
it at least 4 hours before or 8 hours after any of these products.
Do not take Actira with nonsteroidal anti-inflammatory drugs
(NSAIDs) such as Advil, Motrin, and Naprosyn because it may
increase the risk of nerve stimulation and convulsions.
Other drugs to use cautiously while taking Actira include:
Amiodarone (Cordarone)
Antipsychotic drugs such as Haldol, Stelazine, and Thorazine
Erythromycin (E-Mycin, Erythrocin)
Procainamide (Procan SR)
Quinidine (Quinidex)
Sotalol (Betapace)
Tricyclic antidepressants such as Elavil, Norpramin, and Triavil
Warfarin (Coumadin)
You also should avoid Actira if the amount of potassium in
your blood is low. Low potassium can sometimes be caused by
diuretic medications such as Lasix. If you are taking a diuretic
medicine, tell your doctor before taking Actira. In fact,
inform your doctor of all medications you are taking, including
over-the-counter remedies.
Special information if you are pregnant or breastfeeding
The effects of Actira during pregnancy have not been studied.
It should be used during pregnancy only if the benefits outweigh
the possible risk to the unborn baby. If you are expecting,
make sure the doctor is aware of it before you start taking
Actira.
Actira may appear in breast milk and could affect a nursing
infant. If Actira is essential to your health, your doctor
may advise you to discontinue breastfeeding until your treatment
is finished.
Recommended dosages for Actira
ADULTS
Acute Bacterial Sinusitis
The usual dose is one 400-milligram tablet daily for 7 to
14 days.
Acute Bacterial Infection with Chronic Bronchitis
The usual dose is one 400-milligram tablet daily for 5 days.
Pneumonia
The usual dose is one 400-milligram tablet daily for 7 to
14 days.
Skin Infections
The usual dose is one 400-milligram tablet daily for 7 days.
Overdosage of Actira
Any medication taken in excess can have serious consequences.
If you suspect an overdose of Actira, seek medical attention
immediately.
Symptoms of Actira overdose may include:
Convulsions, decreased activity, diarrhea, sleepiness, tremors,
vomiting
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